Would you live here?
Gwynn Griffith does, even though it is an old manufacturing plant in a run-down section of San Antonio. Her story even made it into the New York Times. She loves this house, and I'm pretty sure she fully accepts that she may never see a return on her investment given its location (the Times doesn't say, but I'm thinking it is on the East Side; there used to be a substantial industrial base over there).
Check out the slide show here. And, if you have ever complained about train noise before, make sure you check out the sixth picture.
UPDATE: Alan from Blogonomicon recognizes the place. He says it is on the near South Side. Read what he says about the neighborhood in the comments.